Patents & Publications

Analytical Chemistry

Jackson, P., Pluskal, M. G. and Skea, W.  (in press)

The use of polyacrylamide gel electrophoresis for the enzymatic analysis of acidic glycans labeled with the fluorophore 2-aminoacridone. 

Analytical Biochemistry.

Lopez, M. F., Barry, P., Sawlivich, W. B., Hines, T. and Skea W. M.  1994

High resolution 2-D peptide mapping with subsequent analysis of peptides by microsequencing or lectin binding directly from PVDF membrane blots.

Applied and Theoretical Electrophoresis; 4: 95-102.

Lopez, M., Patton, W., Sawlivich, W., Erdjument-Bromage, H., Barry, P., Gmyrek, K., Hines, T., Tempst, P. and Skea, W.  1994

A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta class of GSTs. 

Biochemica et Biophysica Acta; 1205: 29-38.


Patton, W. F., Lopez, M. F., Barry, P. and Skea, W. M.  1992 

A mechanically strong matrix for protein electrophoresis with enhanced silver staining properties. 

Biotechniques; 12(4): 580-585.

Patton, W. F., Chung-Welch, N., Lopez, M. F., Cambria, R. P., Utterback, B. L. and Skea, W. M.  1991 

Exploring the anomalous electrophoretic migration of simple epithelial keratins using sequence information. 

in Proceedings of the International Meeting on 2-D Electrophoresis, M. Dunn, ed., London, July 16-18, pp 125-129.

Lopez, M. F., Patton, W. F., Utterback, B. L., Chung-Welch, N., Barry, P., Skea, W. M. and Cambria, R. P.  1991 

Effect of various detergents on protein migration in the second dimension of two-dimensional gels. 

Analytical Biochemistry; 199: 35-44.

Patton, W. F., Chung-Welch, N., Lopez, M. F., Cambria, R. P., Utterback, B. L. and Skea, W. M.  1991 

Tris-tricine and tris-borate buffer systems provide better estimates of human mesothelial cell intermediate filament protein molecular weights than the standard tris-glycine system. 

Analytical Biochemistry; 197: 25-33.

Patton, W. F., Pluskal, M. G., Skea, W. M., Buecker, J. L., Lopez, M. F., Zimmermann, R., Belanger, L. M. and Hatch, P. D.  1990

Development of a dedicated two-dimensional gel electrophoresis system that provides optimal pattern reproducibility and polypeptide resolution.  

BioTechniques; 8(5): 518-527.

Skea, W. M.  1989

Process high performance liquid chromatography.

in High Performance Liquid Chromatography, P. R. Brown and R. A. Hartwick, Eds., John Wiley & Sons, New York, pp        479-527.

Doos, W. G., duMoulin, G. C., Jordi, H., Orf, H. W., Seder, R., Skea, W and Sullinger, J.  1988 

Field tests on four state-of-the-art blood chemistry analyzers in a mobile laboratory setting. 

Military Medicine; 153(2): 81-86.


duMoulin, G. C., Skea, W. M.  and Bartolini, B. M.  1986 

Microbiologic assessment of drinking water potability during brigade operations. 

Military Medicine; 151: 570-573.

Skea, W., Dwyer, J., Kierstead, T. and Findeisen, C.  1986 

Scaling column techniques: Simulated process modeling. 

Journal of Analysis and Purification; 1: 50-55.

Kalyanpur, M., Skea, W. and Siwak, M.  1985

Isolation of cephalosporin C from fermentation broths using membrane systems and high performance liquid chromatography.

in Developments in Industrial Microbiology, L. A. Underkofler, Ed., Society for Industrial Microbiology, Arlington, Virginia, vol. 26, pp 455-470.

Dincer, A. K., Kalyanpur, M., Skea, W., Ryan, M. and Kierstead, T.  1984

Continuous on-line monitoring of fermentation processes.

in Developments in Industrial Microbiology, C. H. Nash and L. A. Underkofler, eds., Society for Industrial Microbiology, Arlington, Virginia, vol. 25, pp 603-611.

Dwyer, J., Findeisen, C. and Skea, W.  1984

Chromatographic purification of beta-lactam antibiotics. 

Pharmaceutical Technology; 8(9): 100-112.

Pfeifer, R., Skea, W. M., Waraska, J., Cohen, C. and Burnworth, L.  1981

Protein purification and analysis by HPLC 

in Biological/Biomedical Applications of Liquid Chromatography IV, G. L. Hawk, ed., Marcel Dekker, New York, vol. 20, pp 43-55.

Morris, I. and Skea, W. M.  1978

Products of photosynthesis in natural populations of marine phytoplankton from the Gulf of Maine. 

Marine Biology; 47: 303-312.

Zeldin, M. H., Skea, W. M. and Matteson, D.  1973

Organelle formation in the presence of a protease inhibitor. 

Biochemical Biophysical Research Communications; 52: 544-549.


Food Processing

Haralampu, S.G.  2001

In vivo and in vitro digestion of resistant starch.

in Advanced Dietary Fibre Technology, B.V. McCleary and L. Prosky, eds.

Blackwell Science Ltd., Oxford, England.  pp. 413-423.


Haralampu, S.G.  2000

Resistant starch—a review of the physical properties and biological impact of RS3.

Carbohydrate Polymers.  41: 285-292.


Gross, A. and S.G. Haralampu.  1999

Microcrystalline starch-based product and use in foods.

U.S. Patent 5,962,047


Haralampu, S.G.  1999

Food ingredients used to modulate glucose uptake.

Proceed. Int'l. Symp. Control. Rel. Bioact. Mater.  26:  248-249.


Haralampu, S.G. and A. Gross.  1998

Granular resistant starch and method of making.

U.S. Patent 5,849,090


Feeney, R.D., S.G. Haralampu and A. Gross.  1993

Potato and other food products coated with edible oil barrier films.

U.S. Patent 5,217,736


Haralampu, S.G., S. Sands and A. Gross.  1992

Method for producing an edible prolamine coating from an aqueous latex.

U.S. Patent 5,182,130


Feeney, R.D., S.G. Haralampu and A. Gross.  1992

Method for coating foods with an edible oil barrier film and product thereof.

U.S. Patent 5,126,152


Rahman, A.R. and S.G. Haralampu.  1978

Process for producing compacted, dehydrated uncooked cabbage and product thereof.

U.S. Patent 4,109,026


Mathematical Modeling

Haralampu, S.G.  1986

Using UNIFAC to predict aroma losses in juice concentration. 

in Drying '86, A.S. Mujumdar, ed., Hemisphere Publishing, Washington DC, pp 742-746.


Haralampu, S.G., I. Saguy and M. Karel.  1986

Identification of moisture sensitivity models of packaged materials under simulated storage conditions.

Mathematical Modeling.  7: 1-13.


Haralampu, S.G., I. Saguy and M. Karel.  1986

The performance of a dynamic stability test for moisture sensitivity.

Mathematical Modeling.  7: 15-25.


Haralampu, S.G., I. Saguy and M. Karel.  1985

Estimation of Arrhenius model parameters using three least squares methods.

Journal of Food Processing and Preservation.  9: 129-143.


Haralampu, S.G. and M. Karel.  1983.

Kinetic models for moisture dependence of ascorbic acid and -carotene degradation in dehydrated sweet potato.

Journal of Food Science.  48: 1872-1873.



Haralampu, S.G., C.H. Reynolds, D. Vogel and J. Zindler.  2011

Apparatus for monitoring tire pressure.

U.S. Patent 7,882,732



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